Multi-functional Micro-bioreactor- A powerful tool for teaching and R&D
Classification:
- Description
- Characteristic
- Configuration
- Technical Parameter
- Control System
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B.R.BioCell DW2.6L multifunctional micro stirred tank bioreactor is compact in appearance and powerful in function. It is specially used for early research of culture process, process optimization and strain screening. Its unique design makes it extremely flexible. Various types of stirring paddles can be replaced freely. Glass tanks and single-use plastic tanks can be used interchangeably. It is equipped with a high-precision process control system. All these configurations make B.R.Biocell DW2.6L a powerful tool for scientific research and teaching.
◇ Application scenarios: Microorganisms, mammals, insect cells, plant cells and stem cell culture
◇ Addition mode: batch, feeding or perfusion
◇ Culture process: cell suspension, microcarrier, sheet carrier culture process
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1. Small size, complete configuration, powerful functions and easy operation.
2. Equipped with various types of stirring paddles (large inclined blade paddles, cell lifting paddles, sheet carrier basket paddles, propellers, six flat blade paddles, etc.) to meet the cell suspension, microcarrier, sheet carrier culture process, and achieve multiple uses in one tank.
3. Unique water bath temperature control system, PID temperature control, precise temperature control.
4. Up to 8 culture containers can be used in parallel, and the parameters are displayed on the touch screen at the same time, allowing you to view the real-time parameters of each reactor more intuitively, which is conducive to condition exploration and optimization.
5. Automated control system, real-time monitoring and control of stirring speed, temperature, pH, DO, defoaming, liquid level, feeding, gas mixing, etc. during cell culture, recording and storing data, supporting remote operation.
6. Comply with GMP related regulations, data is complete and traceable, and multi-level user management permissions can be set.
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☆ Tank: high borosilicate glass or plastic container
☆ Industrial PC
☆ Full color touch screen (1024X768)
☆ Servo control system
☆ The agitator adopts magnetic fluid seal
☆ Stirring paddle (large pitched blade paddle, cell lifting paddle, sheet carrier basket paddle, propeller, six flat blade paddle, etc. are optional)
☆ Peristaltic pump
☆ Temperature sensor
☆ Liquid level sensor
☆ Optical pH and DO electrodes, no need for activation, digital transmission, good stability
☆ Mass flow meter
☆ Water bath thermostat
☆ Electronic exhaust condenser
☆ Import filter
☆ Sterilization stent
☆ Sterile sampler (optional)
☆ Disposable sterile connector (optional)
☆ Exhaust gas analyzer (optional)
☆ Turbidity sensor (optional)
☆ No bubble feeding (optional)
☆ Online live cell concentration detection (optional)
☆ Cell retention device (optional)
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Tank: Total volume 2.6L, working volume 0.8~2.0L
Temperature: 5℃ - 80℃ higher than the cooling medium temperature, accuracy ±0.2℃
Stirring: 0-150rpm, accuracy ±1rpm
Ventilation: 4 + 1 gas mixing function, where four gases (Air+O2+N2+CO2) are precisely controlled by rotor flowmeter or mass flowmeter, and the air is inlet from the center of the stirring shaft or the annular microporous distributor; one air pipeline enters from the tank cover, forming a slight positive pressure in the tank head space, which can effectively prevent the generation of bubbles. The air inlet and exhaust port filters are 0.22um filters. The peristaltic pump is equipped with 3 units, which can be expanded to 4 units, with a fixed speed of 60rpm and a variable working cycle, or an optional stepper motor to control 0-300rpm.
pH: 2-12pH, accuracy ±0.02pH
DO: 0-200%, accuracy ±1%
Defoaming: Foam/liquid level electrode, automatic recognition
Sterilization: The tank is placed in a sterilization rack for off-site sterilization
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The BRBioCell DW control system uses Siemens S7-1200PLC (Programmable Logic Controller), 12-inch full-color industrial control touch-screen computer, and 32G hard disk database management to record and store biological reaction processes in real time, meet GMP requirements for traceability of drug production management data, and output files in pre-set report formats.
It provides powerful parameter control, with real-time and historical curve analysis functions; friendly human-machine interface, control status is clear at a glance; modular automatic control, strong flexibility, and comprehensive customer support and services.
The entire system uses industrial Ethernet communication and can be remotely monitored by portable devices; it allows you to control cell culture status and handle alarm events anytime and anywhere; three-level password authorization management and maintenance.
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