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Desktop Glass Tank Bioreactor – Suitable for pilot development and small-scale production

Model B.R.Biocell Volume: 5/7/14L Tank material: high borosilicate glass or plastic container Stirring method: Top mechanical stirring Stirring paddle: large oblique blade paddle, cell lifting paddle, flake carrier basket paddle, propeller, six flat blade paddle, etc. Sterilization method: off-position high-pressure steam sterilization Basic configuration: temperature, speed, PH, dissolved oxygen, liquid level, defoaming, replenishment, tank pressure
  • Description
  • Characteristic
  • Configuration
  • Technical Parameter
  • Control System
  •   B.R.BioCell desktop glass tank bioreactor is rationally designed, precisely manufactured, and powerfully functional. It is specifically used for culture process research, production process optimization, and new process development.

      ◇Application scenarios: Microbial, mammalian, insect cell, plant cell and stem cell culture, seed solution preparation

      ◇ Addition mode: batch, feeding or perfusion

      ◇ Culture process: cell suspension, microcarrier, sheet carrier culture process

  • 1. Glass tank body, easy to observe, complete configuration, easy to operate and powerful functions.

    2. Equipped with various types of stirring paddles (large inclined blade paddles, cell lifting paddles, sheet carrier basket paddles, propellers, six flat blade paddles, etc.) to meet the cell suspension, microcarrier, sheet carrier culture process, and achieve multiple uses in one tank .

    3. Unique water bath temperature control system, PID temperature control, precise temperature control.

    4. Up to 4 culture containers can be used in parallel, and the parameters are displayed on the touch screen at the same time, allowing you to view the real-time parameters of each reactor more intuitively, which is conducive to condition exploration and optimization.

    5. Automated control system, real-time monitoring and control of stirring speed, temperature, pH, DO, defoaming, liquid level, feeding, gas mixing, etc. during cell culture, record and store data, and support remote operation.

    6. Comply with GMP related regulations, data is complete and traceable, and multi-level user management permissions can be set.

  • ☆ Tank: high borosilicate glass or plastic container

    ☆ Industrial PC

    ☆ Full color touch screen (1024X768)

    ☆ Servo control system

    ☆ The agitator adopts magnetic fluid seal

    ☆ Stirring paddle (large pitched blade paddle, cell lifting paddle, sheet carrier basket paddle, propeller, six flat blade paddle, etc. are optional)

    ☆ Peristaltic pump

    ☆ Temperature sensor

    ☆ Liquid level sensor

    ☆ Optical pH and DO electrodes, no need for activation, digital transmission, good stability

    ☆ Mass flow meter

    ☆ Water bath thermostat or jacket water heating

    ☆ Electronic exhaust condenser

    ☆ Import filter

    ☆ Sterilization stent

    ☆ Sterile sampler (optional)

    ☆ Disposable sterile connector (optional)

    ☆ Exhaust gas analyzer (optional)

    ☆ Turbidity sensor (optional)

    ☆ No bubble feeding (optional)

    ☆ Online live cell concentration detection (optional)

    ☆ Cell retention device (optional)

  • B.R.BioCell 5L、7L、14L

    Tank: Total volume 5L, 7L, 14L, working volume is about 75% of the total volume

    Temperature: 5℃ - 80℃ higher than the cooling medium temperature, accuracy ±0.2℃

    Stirring: 0-150rpm, accuracy ±1rpm

    Ventilation: 4 + 1 gas mixing function, where four gases (Air+O2+N2+CO2) are precisely controlled by rotor flowmeter or mass flowmeter, and the air is inlet from the center of the stirring shaft or the annular microporous distributor; one air pipeline enters from the tank cover, forming a slight positive pressure in the tank head space, which can effectively prevent the generation of bubbles. The air inlet and exhaust port filters are both 0.22um filters

    Peristaltic pump: 3 units, expandable to 4 units, fixed speed 60rpm variable duty cycle, or optional stepper motor control 0-300rpm

    pH: 2-12pH, accuracy ±0.02pH

    DO: 0-200%, accuracy ±1%

    Defoaming: Foam/liquid level electrode, automatic recognition

    Sterilization: The tank is placed in a sterilization rack for off-site sterilization

  • The BRBioCell DW control system uses Siemens S7-1200PLC (Programmable Logic Controller), 12-inch full-color industrial control touch-screen computer, and 32G hard disk database management to record and store biological reaction processes in real time, meet GMP requirements for traceability of drug production management data, and output files in pre-set report formats.

    It provides powerful parameter control, with real-time and historical curve analysis functions; friendly human-machine interface, control status is clear at a glance; modular automatic control, strong flexibility, and comprehensive customer support and services.

    The entire system uses industrial Ethernet communication and can be remotely monitored by portable devices; it allows you to control cell culture status and handle alarm events anytime and anywhere; three-level password authorization management and maintenance.

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